Review Article
Study of Protein Biomarkers of Diabetes Mellitus Type 2 and Therapy with Vitamin B1
Table 1
Serum proteins identified in diabetes mellitus.
| Serial number | Category of protein | Name of protein | Expression in diabetics |
| 1 | Cytokines and cytokine-related proteins | Leptin | + | TNF-alpha | + | IL-6 | + |
| 2 | Other immune-related proteins | MCP-1 | + |
| 3 | Proteins involved in fibrinolytic system | PAI-1 | + | Tissue factor | + |
| 4 | Complement and complement-related proteins | Adipsin (complement factor D) | + | ASP | + | Adiponectin | − |
| 5 | Lipids and proteins for lipid metabolism or transport | Lipoprotein lipase (LPL) | + | Apolipoprotein E | + | Apolipoprotein A1, | − | Apolipoprotein A2 | − | Apolipoprotein B | + | Apolipoprotein H | − | Apolipoprotein C1, C2 | − | NEFAs | + | Cholesterol ester transferase protein (CETP) | + |
| 6 | Inflammatory proteins | C-reactive protein (CRP) | + | α-tumor necrosis factor (αTNF) | + |
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