Inhibition of Ceramide De Novo Synthesis Ameliorates Diet Induced Skeletal Muscles Insulin Resistance

Figure 3

Effect of high-fat diet (HFD) feeding (5 weeks) and/or myriocin application (7 days) on sphingomyelin (SM) content in skeletal muscles ( (per group) = 8). M+: rats administered with myriocin. M−: untreated group. Results are expressed as means ± SD.