Polymorphisms of GLP-1 Receptor Gene and Response to GLP-1 Analogue in Patients with Poorly Controlled Type 2 Diabetes

Table 2

The frequencies of missense and silent variants in 36 patients type 2 diabetic subjects.

Marker	Locus	Type/function	MAF	Genotype	Frequency
rs3765467	Exon 4	SNP/missense	0.194 (0.065)	C/T	58/14
				CC/CT/TT	25/8/3
rs761386	Intron between Exons 9 and 10	SNP	0.222 (0.103)	C/T	56/16
				CC/CT/TT	22/12/2
rs5875654	Intron between Exons 10 and 11	InDel	0.222 (0.146)	8/7 GA	56/16
				88/78/77 GA	22/12/2

MAF = minor allele frequency. Bracketed values refer to MAF from HapMap-CHB populations or 1000 Genomes.
STR = short tandem repeat.