Ameliorative Effect of Allopurinol on Vascular Complications of Insulin Resistance

Table 3

The effect of allopurinol (Allo) treatment on insulin resistance (IR) induced BP cycle duration changes measured in seconds compared to control group.

	Total cycle duration	Ejection duration	Diastolic duration	Time to peak
Control group	0.196 ± 0.007	0.069 ± 0.002	0.127 ± 0.007	0.040 ± 0.003
IR group	0.190 ± 0.011	0.062 ± 0.004	0.123 ± 0.01	0.028 ± 0.002
IR-Allo group	0.220 ± 0.012	0.104 ± 0.013^#	0.118 ± 0.010	0.038 ± 0.002
Allo group	0.194 ± 0.009	0.066 ± 0.005	0.129 ± 0.007	0.036 ± 0.004

Values are expressed as the mean ± SEM; = 6–8 animals.
< 0.05, < 0.01, and < 0.001, compared with the corresponding control (C) group values; < 0.05, < 0.01, and < 0.001 compared with the corresponding IR group values, by One-Way ANOVA and Newman-Keuls post hoc test.