Research Article
Cross Talk between Lipid Metabolism and Inflammatory Markers in Patients with Diabetic Retinopathy
Table 2
Intercorrelations between the measured serum parameters. Bold cells denote statistically significant associations.
| | Leptin (ng/mL) | Adiponectin (ng/mL) | Sialic acid (M) | ApoA (g/L) | ApoB (g/L) | Vitamin D (ng/mL) | VEGF (pg/mL) |
IL-1α (pg/mL) |
IL-1β (pg/mL) |
IL-1ra (pg/mL) | IL-4 (pg/mL) | IL-6 (pg/mL) | IL-10 (pg/mL) | TNF-alpha (pg/mL) |
| Leptin (ng/mL) | | | | | | | | | | | | | | | Adiponectin (ng/mL) | +0.095 (p = 0.174) | | | | | | | | | | | | | | Sialic acid (M) | +0.212 (p = 0.002) | −0.054 (p = 0.443) | | | | | | | | | | | | | ApoA (g/L) | +0.036 (p = 0.607) | +0.269 (p = 0.001) | −0.062 (p = 0.378) | | | | | | | | | | | | ApoB (g/L) | +0.026 (p = 0.716) | +0.064 (p = 0.306) | +0.020 (p = 0.774) | +0.392 (p < 0.0001) | | | | | | | | | | | Vitamin D (ng/mL) | −0.123 (p = 0.110) | +0.077 (p = 0.321) | −0.140 (p = 0.071) | +0.191 (p = 0.013) | +0.122 (p = 0.114) | | | | | | | | | | VEGF (pg/mL) | −0.016 (p = 0.815) | −0.084 (p = 0.230) | +0.043 (p = 0.538) | −0.046 (p = 0.509) | +0.012 (p = 0.868) | −0.047 (p = 0.542) | | | | | | | | | IL-1α (pg/mL) | +0.021 (p = 0.773) | +0.103 (p = 0.148) | +0.053 (p = 0.418) | +0.121 (p = 0.088) | +0.170 (p = 0.016) | +0.143 (p = 0.069) | +0.005 (p = 0.995) | | | | | | | | IL-1β (pg/mL) | +0.170 (p = 0.016) | −0.024 (p = 0.740) | +0.020 (p = 0.774) | −0.041 (p = 0.528) | −0.028 (p = 0.691) | −0.150 (p = 0.056) | −0.018 (p = 0.803) | +0.147 (p = 0.041) | | | | | | | IL-1ra (pg/mL) | +0.164 (p = 0.020) | −0.038 (p = 0.592) | +0.120 (p = 0.091) | −0.069 (p = 0.335) | +0.081 (p = 0.254) | +0.002 (p = 0.998) | +0.017 (p = 0.815) | +0.435 (p < 0.0001) | +0.486 (p < 0.001) | | | | | | IL-4 (pg/mL) | +0.077 (p = 0.278) | +0.029 (p = 0.681) | −0.012 (p = 0.868) | −0.001 (p = 0.986) | +0.035 (p = 0.626) | +0.096 (p = 0.226) | +0.001 (p = 0.987) | +0.144 (p = 0.046) | +0.310 (p < 0.0001) | +0.331 (p < 0.0001) | | | | | IL-6 (pg/mL) | +0.086 (p = 0.222) | +0.004 (p = 0.954) | +0.036 (p = 0.610) | +0.065 (p = 362) | +0.241 (p = 0.001) | +0.039 (p = 0.621) | +0.081 (p = 0.250) | +0.280 (p = 0.0001) | +0.072 (p = 0.319) | +0.378 (p < 0.0001) | +0.210 (p = 0.003) | | | | IL-10 (pg/mL) | +0.136 (p = 0.051) | −0.024 (p = 0.731) | +0.055 (p = 0.433) | +0.053 (p = 0.413) | +0.111 (p = 0.112) | −0.016 (p = 0.841) | +0.088 (p = 0.209) | +0.207 (p = 0.003) | +0.266 (p = 0.0001) | +0.273 (p = 0.0001) | +0.299 (p < 0.0001) | +0.225 (p = 0.001) | | | TNF-alpha (pg/mL) | −0.070 (p = 0.321) | −0.042 (p = 0.552) | +0.007 (p = 0.927) | +0.160 (p = 0.023) | +0.312 (p < 0.0001) | +0.120 (p = 0.122) | +0.175 (p = 0.012) | +0.136 (p = 0.056) | +0.007 (p = 0.926) | +0.122 (p = 0.086) | +0.128 (p = 0.075) | +0.381 (p < 0.0001) | +0.175 (p = 0.012) | |
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