The Association of Soluble IGF2R and IGF2R Gene Polymorphism with Type 2 Diabetes
Table 1
Clinical characteristics of the study population.
Normal ( = 297)
IFG/IGT ( = 260)
Unknown DM ( = 97)
P value*
Known DM ( = 145)
value**
Age (year)
61.7 ± 8.1
63.0 ± 7.8
63.0 ± 6.7
NS
60.3 ± 11.0
NS
% female
82.9
83.9
87.8
NS
65.6
<0.01
Weight (kg)
57.9 ± 10.1
61.3 ± 9.8
65.1 ± 10.1
<0.01
64.0 ± 13.1
<0.01
Height (cm)
154.5 ± 7.2
154.1 ± 6.8
153.9 ± 6.0
NS
157.1 ± 9.6
<0.01
BMI (kg/m2)
24.2 ± 3.6
25.8 ± 3.6
27.6 ± 4.4
<0.01
26.1 ± 6.5
<0.01
Fasting plasma glucose (mg/dL)
90.2 ± 6.0
100.5 ± 8.7
129.5 ± 36.9
<0.01
148.4 ± 47.3
<0.01
2 hr glucose (mg/dL)
110.6 ± 16.4
146.5 ± 26.5
263.1 ± 55.1
<0.01
—
—
HOMA-IR
1.5 ± 0.8
2.3 ± 1.4
4.6 ± 3.3
<0.01
5.8 ± 6.3
<0.01
HOMA-B
95.2 ± 57.5
90.4 ± 44.4
95.8 ± 119.8
NS
76.5 ± 5.0
<0.01
Comparison among subjects with no previous history of diabetes. **Comparison between normal and known DM subjects. DM = diabetes mellitus; HOMA = homeostatic model assessment; NS = not significant.
