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Journal of Diabetes Research
Volume 2015, Article ID 236238, 10 pages
http://dx.doi.org/10.1155/2015/236238
Research Article

Topically Applied Connective Tissue Growth Factor/CCN2 Improves Diabetic Preclinical Cutaneous Wound Healing: Potential Role for CTGF in Human Diabetic Foot Ulcer Healing

1Sydney Medical School and Charles Perkins Centre, University of Sydney, Sydney, NSW 2006, Australia
2Department of Biomedical Engineering, School of Aerospace, Mechanical and Mechatronic Engineering, University of Sydney, Sydney, NSW 2006, Australia
3Department of Endocrinology, Royal Prince Alfred Hospital, Camperdown, NSW 2050, Australia

Received 27 September 2014; Revised 23 January 2015; Accepted 2 February 2015

Academic Editor: Solomon Tesfaye

Copyright © 2015 F. R. Henshaw et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [20 citations]

The following is the list of published articles that have cited the current article.

  • Andrew Leask, “Fixing a hole: CCN2 closes chronic wounds,” Journal of Cell Communication and Signaling, 2015. View at Publisher · View at Google Scholar
  • Frank L Bowling, S Tawqeer Rashid, and Andrew J M Boulton, “Preventing and treating foot complications associated with diabetes mellitus.,” Nature reviews. Endocrinology, vol. 11, no. 10, pp. 606–16, 2015. View at Publisher · View at Google Scholar
  • Hongling Li, Cong Cao, Ai Huang, and Yi Man, “Comment on “Topically Applied Connective Tissue Growth Factor/CCN2 Improves Diabetic Preclinical Cutaneous Wound Healing: Potential Role for CTGF in Human Diabetic Foot Ulcer Healing”,” Journal of Diabetes Research, vol. 2015, pp. 1–3, 2015. View at Publisher · View at Google Scholar
  • J. A. Epps, and N. A. Smart, “Remote ischaemic conditioning in the context of type 2 diabetes and neuropathy: the case for repeat application as a novel therapy for lower extremity ulceration,” Cardiovascular Diabetology, vol. 15, no. 1, 2016. View at Publisher · View at Google Scholar
  • Alegna P. Baliano, Elisangela F. Pimentel, Aline R. Buzin, Tainã Z. Vieira, Wanderson Romão, Lilian V. Tose, Dominik Lenz, Tadeu U. de Andrade, Marcio Fronza, Tamara P. Kondratyuk, and Denise C. Endringer, “Brown seaweed Padina gymnospora is a prominent natural wound-care product,” Revista Brasileira de Farmacognosia, 2016. View at Publisher · View at Google Scholar
  • Manikarna Dinda, Swagata Mazumdar, Saurabh Das, Durba Ganguly, Uma B Dasgupta, Ananya Dutta, Kuladip Jana, and Parimal Karmakar, “ The Water Fraction of Calendula officinalis Hydroethanol Extract Stimulates In Vitro and In Vivo Proliferation of Dermal Fibroblasts in Wound Healing ,” Phytotherapy Research, 2016. View at Publisher · View at Google Scholar
  • Satoshi Kubota, and Masaharu Takigawa, “Ccn,” Encyclopedia of Signaling Molecules, pp. 1–15, 2016. View at Publisher · View at Google Scholar
  • Amena Mahmood, Ambrish K. Tiwari, Kazım Şahin, Ömer KÜÇÜK, and Shakir Ali, “Triterpenoid saponin-rich fraction of Centella asiatica decreases IL-1β andNF-κB, and augments tissue regeneration and excision wound repair,” Turkish Journal Of Biology, vol. 40, pp. 399–409, 2016. View at Publisher · View at Google Scholar
  • Ashang Luwang Laiva, Fergal J. O'Brien, and Michael B. Keogh, “Innovations in gene and growth factor delivery systems for diabetic wound healing,” Journal of Tissue Engineering and Regenerative Medicine, 2017. View at Publisher · View at Google Scholar
  • Wenxia Yan, Hanping Liu, Xiaoyuan Deng, Ying Jin, Ning Wang, and Jing Chu, “Acellular dermal matrix scaffolds coated with connective tissue growth factor accelerate diabetic wound healing by increasing fibronectin through PKC signalling pathway,” Journal of Tissue Engineering and Regenerative Medicine, 2017. View at Publisher · View at Google Scholar
  • Satoshi Kubota, and Masaharu Takigawa, “Ccn,” Encyclopedia of Signaling Molecules, pp. 814–827, 2017. View at Publisher · View at Google Scholar
  • Alessandra Moore, Clement Marshall, and Michael Longaker, “Minimizing Skin Scarring through Biomaterial Design,” Journal of Functional Biomaterials, vol. 8, no. 1, pp. 3, 2017. View at Publisher · View at Google Scholar
  • Norhayati Ahmad, and Ahmadi Yusmin, “Effect of thymoquinone on wound healing in alloxan-induced diabetic rats,” Asian Journal of Pharmaceutical and Clinical Research, vol. 10, no. 9, pp. 242–245, 2017. View at Publisher · View at Google Scholar
  • Stephen M. Twigg, “Regulation and bioactivity of the CCN family of genes and proteins in obesity and diabetes,” Journal of Cell Communication and Signaling, 2018. View at Publisher · View at Google Scholar
  • Wenbin Gong, Tao Cheng, Quanguo Liu, Qianru Xiao, and Junsheng Li, “Surgical repair of abdominal wall defect with biomimetic nano/microfibrous hybrid scaffold,” Materials Science and Engineering: C, vol. 93, pp. 828–837, 2018. View at Publisher · View at Google Scholar
  • Amal D. Premarathna, T.H. Ranahewa, S.K. Wijesekera, R.R.M.K.K. Wijesundara, Anura P. Jayasooriya, Viskam Wijewardana, and R.P.V.J. Rajapakse, “Wound Healing properties of Aqueous Extracts of Sargassum illicifolium: An In Vitro Assay,” Wound Medicine, 2018. View at Publisher · View at Google Scholar
  • Kunihiro Hayakawa, Keigo Ikeda, Maki Fujishiro, Yuko Yoshida, Takuya Hirai, Hiroshi Tsushima, Tomoko Miyashita, Shinji Morimoto, Yasushi Suga, Kenji Takamori, Hideoki Ogawa, and Iwao Sekigawa, “Connective Tissue Growth Factor Neutralization Aggravates the Psoriasis Skin Lesion: The Analysis of Psoriasis Model Mice and Patients,” Annals of Dermatology, vol. 30, no. 1, pp. 47, 2018. View at Publisher · View at Google Scholar
  • Sungjoo Park, Eunsu Ko, Jun Hyoung Lee, Yoseb Song, Chang-Hao Cui, Jingang Hou, Byeong Min Jeon, Hun Sik Kim, and Sun Chang Kim, “Gypenoside LXXV Promotes Cutaneous Wound Healing In Vivo by Enhancing Connective Tissue Growth Factor Levels Via the Glucocorticoid Receptor Pathway,” Molecules, vol. 24, no. 8, pp. 1595, 2019. View at Publisher · View at Google Scholar
  • Christopher G. Elliott, Jiarong Wang, John T. Walker, Sarah Michelsons, Joy Dunmore-Buyze, Maria Drangova, Andrew Leask, and Douglas W. Hamilton, “Periostin and CCN2 Scaffolds Promote the Wound Healing Response in the Skin of Diabetic Mice,” Tissue Engineering Part A, 2019. View at Publisher · View at Google Scholar
  • Amir Hossein Siadat, and Roslyn Rivkah Isseroff, “Prolotherapy: Potential for the Treatment of Chronic Wounds?,” Advances in Wound Care, 2019. View at Publisher · View at Google Scholar