Topically Applied Connective Tissue Growth Factor/CCN2 Improves Diabetic Preclinical Cutaneous Wound Healing: Potential Role for CTGF in Human Diabetic Foot Ulcer Healing
Wound closure data in diabetic and nondiabetic (control) rats, each treated with topical rhCTGF or PBS alone.
|Results are shown as mean ± SEM. * versus the same day diabetic wounds + PBS (DM + PBS alone), by ANOVA. The main finding was that ulcer area was significantly reduced on days 7, 10, and 14 in the CTGF treated diabetic group (D + CTGF) compared with the non-rhCTGF treated diabetic group (D + PBS alone).|