Research Article

Topically Applied Connective Tissue Growth Factor/CCN2 Improves Diabetic Preclinical Cutaneous Wound Healing: Potential Role for CTGF in Human Diabetic Foot Ulcer Healing

Table 2

Wound breaking strength data in all groups.

Young’s modulusTear strengthTear strainUltimate strengthFinal strain

C + PBS alone0.93 ± 0.090.56 ± 0.061.17 ± 0.101.06 ± 0.013.45 ± 0.22*
DM + PBS alone0.87 ± 0.130.46 ± 0.050.71 ± 0.060.81 ± 0.132.20 ± 0.16
C + CTGF1.21 ± 0.110.53 ± 0.051.04 ± 0.100.89 ± 0.063.08 ± 0.27*
DM + CTGF1.01 ± 0.170.53 ± 0.050.87 ± 0.180.86 ± 0.102.32 ± 0.22

Data are mean ± SD; each * versus DM + PBS, by ANOVA.