Renal Kallikrein Activation and Renoprotection after Dual Blockade of Renin-Angiotensin System in Diet-Induced Diabetic Nephropathy

Figure 1

The effect of benazepril and irbesartan on the levels of 24 h urine protein (a), BUN (b), and Cr (c); CN: normal control group, group 1; DN: diabetic nephropathy control group, group 2; Ben-10, group 3 (benazepril 10 mg/kg/d); Irb-30, group 4 (irbesartan 30 mg/kg/d); and Ben-10 and Irb-30, group 5; and compared with group 1, ; compared with group 2, ^#; compared with group 3, ^◆; compared with group 4, ^▼; BUN: blood urea nitrogen; Cr: serum creatinine.

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(b)

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