Review Article

Role of Electrophysiology in the Early Diagnosis and Follow-Up of Diabetic Retinopathy

Table 1

Standard full field ERG protocols and parameters according to ISCEV.

ERG testAdaptation/timeStimulus range (cdsm−2)Interstimulus time (s)Main physiological generator

Scotopic ERGDark adapted/≥20 min0.02–0.032.0b-wave: rods
Massive ERGDark adapted/≥20 min6.7–8.410a-wave: photoreceptors 
b-wave: bipolar cells
Oscillatory potentialsDark adapted/≥20 min6.7–8.410Middle retinal layer and vascular function
Photopic ERGLight adapted (30 cdm−2)/≥10 min2.7–3.40.5a-wave: cones 
b-wave: bipolar cells
Flicker-ERGLight adapted (30 cdm−2)/≥10 min2.7–3.40.030–0.036Cones