Antidiabetic and Renoprotective Effects of Cladophora glomerata Kützing Extract in Experimental Type 2 Diabetic Rats: A Potential Nutraceutical Product for Diabetic Nephropathy

Figure 2

Micrographs of conventional Hematoxylin and Eosin (H&E) staining of rat kidneys. A sagittal half of kidney from each experimental group was removed, fixed, embedded, cut, and stained by H&E (original magnification 200x for all panels). The data were repeated at least 3 times from separate sets of animals. The results were analyzed using bright-field microscopy. (a) Normal (ND), (b) normal diet supplemented with CGE (ND + CGE), (c) T2DM (DM), (d) T2DM treated with metformin (DM + metformin), and ((e) and (f)) T2DM supplemented with CGE (DM + CGE). Arrow “B” in all panels indicates Bowman’s capsule space. Arrow labeled “P” indicates the proximal tubular epithelial cells and the tubular lumen space. Asterisk () indicates infiltration of blood cells and lymphocytes. Glomerulus (G), proximal tubular epithelial cells and the tubular lumen space (P), and glomerular basement membrane (GBM).

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