Research Article
Impact of Inherited Prothrombotic Disorders on the Long-Term Clinical Outcome of Percutaneous Transluminal Angioplasty in Patients with Diabetes
Table 3
Genotype frequencies with odds ratios.
| | Polymorphism | Genotype | Unsuccessful PTA ( = 75) | Successful PTA
( = 58) | Control
( = 65) | OR
unsuccessful versus successful PTA groups | OR
unsuccessful PTA versus control group |
| | | GG | 65 (86.7%) | 57 (98.3%) | 63 (96.9%) | | | | Leiden | GA | 10 (13.3%) | 1 (1.7%) | 2 (3.1%) | 8.8 (1.1–70.6) | 9.8 (1.2–79.2) | | G1691A | AA | 0 (0%) | 0 (0%) | 0 (0%) | = 0.041 | = 0.032 |
| | | GG | 66 (88%) | 56 (96.6%) | 64 (98.5%) | | | | Prothrombin | GA | 9 (12%) | 2 (3.4%) | 1 (1.5%) | 3.8 (0.8–18.4) | 4.3 (0.9–20.7) | | G20210A | AA | 0 (0%) | 0 (0%) | 0 (0%) | = 0.095 | = 0.069 |
| | | GG | 39 (52%) | 33 (56.9%) | 31 (47.7%) | | | | MTHFR | GA | 25 (33.3%) | 20 (34.5%) | 30 (46.2%) | 1.2 (0.6–2.4) | 0.8 (0.4–1.6) | | C677T | AA | 11 (14.7%) | 5 (8.6%) | 4 (6.1%) | = 0.57 | = 0.61 |
| | | GG | 32 (42.7%) | 25 (43.1%) | 29 (44.6%) | | | | MTHFR | GA | 33 (44%) | 25 (43.1%) | 31 (47.7%) | 1.8 (0.6–5.6) | 1.1 (0.6–2.1) | | C1298A | AA | 10 (13.3%) | 8 (13.8%) | 5 (7.7%) | = 0.29 | = 0.81 |
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