Research Article

Overweight and Obesity Based on Four Reference Systems in 18,382 Paediatric Patients with Type 1 Diabetes from Germany and Austria

Table 1

Clinical characteristics, HbA1c level, and insulin therapy of T1D study participants. Data are given for the years 2000, 2004, 2009, and 2013.

Year of measurement
2000200420092013

Number of participants9,46113,01416,01118,382<0.001
Male (%)51.852.252.952.5<0.001
Age (years)11.8 ± 3.812.0 ± 3.912.0 ± 3.912.2 ± 3.9<0.0001
Age at T1D onset (years)7.6 ± 3.87.6 ± 3.97.5 ± 4.07.5 ± 4.0<0.0001
Diabetes duration (years)4.2 ± 3.54.4 ± 3.64.5 ± 3.64.6 ± 3.7<0.0001
Weight (kg)46.7 ± 18.448.5 ± 19.448.7 ± 19.849.2 ± 19.6<0.0001
Height (cm)150.4 ± 21.7151.2 ± 22.2151.9 ± 22.3152.7 ± 22.1<0.0001
BMI (kg/m2)19.6 ± 3.420.0 ± 3.820.0 ± 3.820.0 ± 3.9<0.0001
HbA1c (mmol/mol)64.2 ± 19.562.9 ± 17.863.4 ± 16.462.3 ± 16.3<0.05
Insulin dose/weight (U/kg/d)0.79 ± 0.290.84 ± 0.310.92 ± 0.340.95 ± 0.30<0.0001
CT (%)33.017.99.35.1<0.0001
MDI (%)63.570.858.351.1<0.0001
CSII (%)3.511.332.443.8<0.0001

Unadjusted mean values ± SD, values obtained from a regression model adjusted for age, gender, and diabetes duration, and values for trend.
CT: conventional insulin treatment, MDI: multiple daily injections, and CSII: continuous subcutaneous insulin infusion.