Journal of Diabetes Research / 2015 / Article / Tab 2

Research Article

Alteration of Mevalonate Pathway in Proliferated Vascular Smooth Muscle from Diabetic Mice: Possible Role in High-Glucose-Induced Atherogenic Process

Table 2

Sequences of forward and reverse primer.

cDNAForward primerReverse primer

HMGR5-GAATGCAGAGAAAGGTGCAA-35-CACCACGTTCATGAGTTTCC-3
FPPS5-GCACTGACATCCAGGACAAC-35-TAAGATCTGGCGCTGTTGAG-3
SQS5-CAAGCAGGTCATCTCCAAGA-35-GCAGCCAAGAGCATGATAAA-3
GGPPS5-TGGAACTTCATCAGGGACAA-35-CCTGTCTTCTGCAACACCAT-3
FNT-β5-TGGCAGTAATCCTGGAACTG-35-GAGCTCGCTGTGACTGTAGC-3
GGT-1β5-GCTAAATGGCCAGACAGTCA-35-CAAATCCCACTCTCCTCCAT-3
β-actin5-CTCCATCCTGGCCTCGCTGT-35-GCTGTCACCTTCACCGTT-3

HMGR, 3-hydroxy-3-methylglutaryl-coenzyme A reductase; FPPS, farnesyl pyrophosphate synthase; SQS, squalene synthase; GGPPS, geranylgeranyl pyrophosphate synthase; FNT-β, farnesyltransferase-β; GGT-1β, geranylgeranyltransferase-1β.