Diabetes-Resistant NOR Mice Are More Severely Affected by Streptozotocin Compared to the Diabetes-Prone NOD Mice: Correlations with Liver and Kidney GLUT2 Expressions

Figure 5

Western blot analysis and immunohistochemical stainings of GLUT2 expressions in the livers and kidneys of non-STZ treated NOD and NOR mice. Representative images are shown demonstrating GLUT2 expression levels in livers (upper panel) and kidneys (lower panel) of NOD and NOR mice via western blot (left) and immunohistochemical stainings (right), prior to STZ application (day 0). Hematoxylin counterstaining was performed following anti-GLUT2 antibody application. Immunohistochemistry images show the corresponding tissues at 10x magnification on the left side, and at 40x magnification in the middle depictions. Arrows are placed for comparison of the staining intensities. Control tissues, treated with secondary antibody only, are shown at right.