The Protective Effect of Radix Polygoni Multiflori on Diabetic Encephalopathy via Regulating Myosin Light Chain Kinase Expression

Figure 1

The representative photos of hippocampal tissue in rats. (A) Control rat; (B) diabetic rat. The neurons in rat hippocampal tissue (mainly pyramidal cells) in control rat group are round or oval in shape, with large and lightly stained cytoplasm also round in shape and orderly arranged nucleus. In diabetes rat group the morphology of the neurons was obviously abnormal in hippocampal tissue. The number of neurons decreased, cells were swelling, and nuclear fragmentation or disappearance was observed, as in cell apoptosis.