[Retracted] Small Molecule Kaempferol Promotes Insulin Sensitivity and Preserved Pancreatic β-Cell Mass in Middle-Aged Obese Diabetic Mice

Figure 2

Kaempferol supplementation reduced blood glucose, HbA1c, and insulin concentrations and improved insulin sensitivity in HF diet-fed mice. (a) Fasting blood glucose levels were measured at indicated time points of dietary treatment. GTT (b) and ITT (d) were performed as described in Section 2. The area under the curve (AUC) for GTT (c) and ITT (e) was calculated. (f) Plasma insulin levels were measured using an ELISA kit. Data are shown as means ± SE (). versus SD-fed mice (C); versus HF-fed mice. C: standard diet; HF: high-fat diet; HF + K1: HF diet containing 0.01% kaempferol; HF + K2: HF diet supplemented with 0.05% kaempferol.

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