[Retracted] Small Molecule Kaempferol Promotes Insulin Sensitivity and Preserved Pancreatic β-Cell Mass in Middle-Aged Obese Diabetic Mice

Figure 6

Dietary intake of kaempferol ameliorated hyperglycemia in STZ-induced obese diabetic mice. Male C57BL/6 mice (10-month-old) were fed a HF diet or HF diet containing 0.05% kaempferol (HF + K) in the diet for 6 weeks prior to administration of STZ (40 mg/kg for 3 consecutive days) and continued on the same diet for 4 weeks. Age-matched mice were fed a SD diet (C). Fasting (a) and nonfasting blood glucose levels (b) were monitored biweekly throughout the study. (c) Plasma insulin levels in fasted mice were measured by ELISA. Data are means ± SE ( mice/group). versus healthy control (C); versus STZ alone-treated mice.

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