[Retracted] Small Molecule Kaempferol Promotes Insulin Sensitivity and Preserved Pancreatic β-Cell Mass in Middle-Aged Obese Diabetic Mice

Figure 7

Kaempferol supplementation preserved pancreatic β-cell mass in STZ-induced diabetic mice. (a) Pancreas from mice given a SD diet (C), HF diet and STZ administration (HF + STZ), and HF + STZ supplemented with 0.05% kaempferol (HF + STZ + K) were isolated and weighed. (b) Fixed pancreas was then sectioned and fluorescently stained with insulin. (c) The β-cell mass was determined as described in Section 2. Data are shown as means ± SE ( mice/group). (d) Insulin content in the pancreas was measured by ELISA and normalized to protein concentration in the same sample. Data are expressed as means ± SEM (-6 mice/group). versus healthy control (C); versus STZ alone-treated mice.

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