Research Article
Elevated Urinary Connective Tissue Growth Factor in Diabetic Nephropathy Is Caused by Local Production and Tubular Dysfunction
Figure 4
Urinary excretion of intrarenally produced CTGF correlates with the degree of tubular dysfunction. (a) Tight linear correlation between intrarenally derived uCTGF and (, , slope = ) suggests that tubular reabsorption failure is a major determinant of intrarenally derived uCTGF. (b) Cortical CTGF mRNA levels correlate with the intrarenally derived urinary CTGF (uCTGF), , . (c) Medullary CTGF expression does not correlate with intrarenally derived uCTGF.
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