Research Article

Effect of Global ATGL Knockout on Murine Fasting Glucose Kinetics

Table 2

Glucose appearance and Cori cycling fluxes in WT and ATGL−/− mice based on plasma glucose 13C-isotopomer analysis. Data are expressed as mean ± SEM.

Glucose fluxesWTATGL−/−

Glucose (μmol/kg/min)70.8 ± 6.778.7 ± 10.6
Glucose (μmol/kg/min)70.8 ± 6.778.7 ± 10.6
EGP (μmol/kg/min)66.4 ± 6.673.1 ± 10.3
Absolute Cori cycle flux (μmol/kg/min)56.6 ± 5.566.9 ± 12.5
Fractional Cori cycle flux (% of )79.9 ± 2.882.0 ± 6.6