Journal of Diabetes Research / 2015 / Article / Fig 4

Research Article

Nutrient Induced Type 2 and Chemical Induced Type 1 Experimental Diabetes Differently Modulate Gastric GLP-1 Receptor Expression

Figure 4

Different frequency of GLP-1R immunoreactive glandular cells in principal glands of diabetic PO and SPD rats. Frequency of GLP-1R immunoreactive cells was determined by quantitative immunohistomorphological analysis in neck, mid, and bottom areas of principal glands. (a) A significant increase of GLP-1R bearing parietal cells in the neck area of principal glands in diabetic PO (black bars) as compared to control animals (white bars) (). (b) A significant decrease in GLP-1R bearing parietal cells in diabetic SPD compared with control animals (). Data are presented as mean ± SD.

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