Effects of Glucose Concentration on Propofol Cardioprotection against Myocardial Ischemia Reperfusion Injury in Isolated Rat Hearts

Figure 3

Effect of low glucose (LG) and glucose (G) on endothelin-1 (ET-1) concentration and coronary perfusion pressure (CPP). ET-1 release and CPP were significantly increased in LG as compared to G (). Propofol significantly reduced cardiac ET-1 and CPP in G but not in LG. TMZ facilitated propofol induced reduction in ET-1 and CPP in LG but did not in G. Re-10 is abbreviation of 10 min after reperfusion. Values are presented as mean ± SEM. per group. versus BS20; versus LG; versus LG+P.

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