Research Article

Association of a Large Panel of Cytokine Gene Polymorphisms with Complications and Comorbidities in Type 2 Diabetes Patients

Table 2

Clinical and laboratorial characteristics in T2D patients considering nephropathy (DNP).

VariablesDiabetic nephropathy
Yes ()No ()

Age (years)58.00 (13.00)50.50 (9.00)<0.0001
Gender (male/female) %21.25/78.7510.00/90.000.348
BMI (Kg/m2)30.48 ± 6.0640.55 ± 5.23<0.0001
Hypertension (yes/ no) %90.00/10.00100.00/00.204
Dyslipidemia (yes/no) %96.25/3.7585.00/15.000.092
Fasting glucose (mg/dL)143.00 (97.50)117.00 (55.50)0.027
Postprandial glucose (mg/dL)214.00 (107.50)144.50 (122.25)0.045
HbA1c %9.24 ± 1.887.73 ± 1.840.006
T2D onset (years) %
 ≤511.54b47.370.001
 5–1014.1015.79
 ≥1074.36a36.84

BMI: body mass index and HbA1c: glycated hemoglobin.
Normal variables (BMI and HbA1c): the data are shown as mean ± standard deviation.
No normal variables (age, fasting glucose, and postprandial glucose): the data are shown as median (interquartile range).
Categorical variables (gender, hypertension, dyslipidemia, and T2D onset): the data are shown as “percentage of total.”
was considered statistically significant.
aMore frequent; bless frequent, residual analysis.