Association of a Large Panel of Cytokine Gene Polymorphisms with Complications and Comorbidities in Type 2 Diabetes Patients
Table 4
Haplotype distribution of IL-10 promoter gene (-1082G/A, -819T/C, and -512C/A) in T2D patients considering complications and comorbidities.
T2D complications/comorbidities
Haplotypes
a
b
c
ACC%
ATA%
GCC%
Retinopathy
Yes ()
31.07
34.08
34.08
0.778
0.563
0.778
No ()
34.86
29.03
35.98
Nephropathy
Yes ()
32.52
33.11
33.73
0.832
0.750
0.916
No ()
32.58
29.92
37.42
Neuropathy
Yes ()
29.77
38.08
30.94
0.670
0.300
0.550
No ()
34.22
28.28
37.44
Hypertension
Yes ()
34.06
30.30
35.62
0.418
0.204
0.418
No (
12.71
55.79
24.54
Dyslipidemia
Yes ()
32.36
32.22
34.82
1.000
1.000
1.000
No ()
34.02
32.46
32.54
BMI
<30 ()
28.54
37.36
32.82
0.480
0.344
0.825
≥30 ()
35.36
28.43
36.19
BMI (body mass index): Kg/m2. was considered statistically significant. a: ACC versus (ATA + GCC). b: ATA versus (ACC + GCC). c: GCC versus (ACC + ATA).
