Changes in Plasma Levels of N-Arachidonoyl Ethanolamine and N-Palmitoylethanolamine following Bariatric Surgery in Morbidly Obese Females with Impaired Glucose Homeostasis
Table 1
Pre- and postoperative clinical and biochemical measurements.
Measurement
Preoperative ()
Postoperative ()
Weight (kg)
160.2 (44.2)
124.8 (29.4)
<0.001
BMI (kg/m2)
57.3 (14.1)
45.4 (10.1)
<0.001
Waist (cm)
143.7 (21.5)
123.4 (20.1)
<0.001
Systolic BP (mmHg)
133 (18)
128 (16)
0.19
Diastolic BP (mmHg)
79 (9)
75 (10)
0.06
Cholesterol (mmol/L)
4.2 (0.9)
3.9 (1.1)
0.26
LDL-C (mmol/L)
2.2 (0.8)
2.1 (0.9)
0.73
HDL-C (mmol/L)
1.2 (0.3)
1.1 (0.3)
0.08
Triglyceride (mmol/L)
1.7 (0.9)
1.4 (0.4)
0.18
HbA1c (%)
7.2 (1.5)
6.1 (1.3)
0.02
HbA1c (mmol/L)
55 (43.1)
43 (37.3)
0.02
Fasting glucose (mmol/L)
7.8 (3.3)
6.0 (3.1)
0.13
2-hour glucose (mmol/L)
12.7 (4.9)
8.3 (5.9)
0.01
Fasting insulin (IU/mL)
27.9 (16.2)
11.4 (6.7)
0.002
Fasting C-peptide (ng/mL)
3.6 (1.5)
2.9 (1.5)
0.10
HOMA %S
305.8 (208.3)
617.5 (492.5)
0.03
HOMA- IR
0.4667 (0.3016)
0.3600 (0.4154)
0.32
C-pep: Insulin ratio
0.1744 (0.0996)
0.2741 (0.1246)
0.001
AEA (pmol/mL)*
0.21 (0.04)
0.19 (0.04)
0.33
OEA (pmol/mL)*
1.05 (0.13)
0.93 (0.18)
0.25
PEA (pmol/mL)*
0.83 (0.09)
0.74 (0.09)
0.10
2-AG (pmol/mL)*
5.0 (1.55)
4.2 (1.40)
0.14
*Geometric mean and approximate standard deviation shown for log transformed data.
