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Journal of Diabetes Research
Volume 2015, Article ID 728127, 9 pages
http://dx.doi.org/10.1155/2015/728127
Research Article

Flow Mediated Dilatation Is Reduced with the Progressive Stages of Glomerular Filtration Rate and Albuminuria in Type 2 Diabetic Patients without Coronary Heart Disease

1Department of Diabetes, Metabolism and Kidney Disease, Edogawa Hospital, 2-24-18 Higashikoiwa, Edogawa, Tokyo 133-0052, Japan
2Laboratory Department, Edogawa Hospital, 2-24-18 Higashikoiwa, Edogawa, Tokyo 133-0052, Japan
3Department of Cardiology, Edogawa Hospital, 2-24-18 Higashikoiwa, Edogawa, Tokyo 133-0052, Japan

Received 8 December 2014; Revised 6 April 2015; Accepted 17 April 2015

Academic Editor: Khalid M. Elased

Copyright © 2015 Hiroyuki Ito et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. H. Taniwaki, T. Kawagishi, M. Emoto et al., “Correlation between the intima-media thickness of the carotid artery and aortic pulse-wave velocity in patients with type 2 diabetes: vessel wall properties in type 2 diabetes,” Diabetes Care, vol. 22, no. 11, pp. 1851–1857, 1999. View at Publisher · View at Google Scholar · View at Scopus
  2. R. Kawamori, Y. Yamasaki, H. Matsushima et al., “Prevalence of carotid atherosclerosis in diabetic patients. Ultrasound high-resolution B-mode imaging on carotid arteries,” Diabetes Care, vol. 15, no. 10, pp. 1290–1294, 1992. View at Publisher · View at Google Scholar · View at Scopus
  3. H. Ito, Y. Komatsu, M. Mifune et al., “The estimated GFR, but not the stage of diabetic nephropathy graded by the urinary albumin excretion, is associated with the carotid intima-media thickness in patients with type 2 diabetes mellitus: a cross-sectional study,” Cardiovascular Diabetology, vol. 9, article 18, 2010. View at Publisher · View at Google Scholar · View at Scopus
  4. R. Ross, “The pathogenesis of atherosclerosis: a perspective for the 1990s,” Nature, vol. 362, no. 6423, pp. 801–809, 1993. View at Publisher · View at Google Scholar · View at Scopus
  5. R. Ross, “Atherosclerosis—an inflammatory disease,” The New England Journal of Medicine, vol. 340, no. 2, pp. 115–126, 1999. View at Publisher · View at Google Scholar · View at Scopus
  6. M. E. Widlansky, N. Gokce, J. F. Keaney Jr., and J. A. Vita, “The clinical implications of endothelial dysfunction,” Journal of the American College of Cardiology, vol. 42, no. 7, pp. 1149–1160, 2003. View at Publisher · View at Google Scholar · View at Scopus
  7. D. H. Endemann and E. L. Schiffrin, “Nitric oxide, oxidative excess, and vascular complications of diabetes mellitus,” Current Hypertension Reports, vol. 6, no. 2, pp. 85–89, 2004. View at Publisher · View at Google Scholar · View at Scopus
  8. D. Tousoulis, C. Antoniades, and C. Stefanadis, “Evaluating endothelial function in humans: a guide to invasive and non-invasive techniques,” Heart, vol. 91, no. 4, pp. 553–558, 2005. View at Publisher · View at Google Scholar · View at Scopus
  9. H. Tomiyama, C. Matsumoto, J. Yamada et al., “The relationships of cardiovascular disease risk factors to flow-mediated dilatation in Japanese subjects free of cardiovascular disease,” Hypertension Research, vol. 31, no. 11, pp. 2019–2025, 2008. View at Publisher · View at Google Scholar · View at Scopus
  10. H. Tomiyama, T. Kohro, Y. Higashi et al., “A multicenter study design to assess the clinical usefulness of semi-automatic measurement of flow-mediated vasodilatation of the brachial artery,” International Heart Journal, vol. 53, no. 3, pp. 170–175, 2012. View at Publisher · View at Google Scholar · View at Scopus
  11. J. Yeboah, A. R. Folsom, G. L. Burke et al., “Predictive value of brachial flow-mediated dilation for incident cardiovascular events in a population-based study: the multi-ethnic study of atherosclerosis,” Circulation, vol. 120, no. 6, pp. 502–509, 2009. View at Publisher · View at Google Scholar · View at Scopus
  12. J. Yeboah, J. R. Crouse, F.-C. Hsu, G. L. Burke, and D. M. Herrington, “Brachial flow-mediated dilation predicts incident cardiovascular events in older adults: the cardiovascular health study,” Circulation, vol. 115, no. 18, pp. 2390–2397, 2007. View at Publisher · View at Google Scholar · View at Scopus
  13. R. T. Ras, M. T. Streppel, R. Draijer, and P. L. Zock, “Flow-mediated dilation and cardiovascular risk prediction: a systematic review with meta-analysis,” International Journal of Cardiology, vol. 168, no. 1, pp. 344–351, 2013. View at Publisher · View at Google Scholar · View at Scopus
  14. M.-D. Enderle, N. Benda, R.-M. Schmuelling, H. U. Haering, and M. Pfohl, “Preserved endothelial function in IDDM patients, but not in NIDDM patients, compared with healthy subjects,” Diabetes Care, vol. 21, no. 2, pp. 271–277, 1998. View at Publisher · View at Google Scholar · View at Scopus
  15. R. M. A. Henry, I. Ferreira, P. J. Kostense et al., “Type 2 diabetes is associated with impaired endothelium-dependent, flow-mediated dilation, but impaired glucose metabolism is not: the Hoorn Study,” Atherosclerosis, vol. 174, no. 1, pp. 49–56, 2004. View at Publisher · View at Google Scholar · View at Scopus
  16. B. M. Nair, V. Viswanathan, C. Snehalatha, R. S. Mohan, and A. Ramachandran, “Flow mediated dilatation and carotid intimal media thickness in South Indian type 2 diabetic subjects,” Diabetes Research and Clinical Practice, vol. 65, no. 1, pp. 13–19, 2004. View at Publisher · View at Google Scholar · View at Scopus
  17. K. Tsuchiya, C. Nakayama, F. Iwashima et al., “Advanced endothelial dysfunction in diabetic patients with multiple risk factors; importance of insulin resistance,” Journal of Atherosclerosis and Thrombosis, vol. 14, no. 6, pp. 303–309, 2007. View at Publisher · View at Google Scholar · View at Scopus
  18. K. Sogawa, T. Nagaoka, I. Tanano et al., “Association between diabetic retinopathy and flow-mediated vasodilation in type 2 DM,” Current Eye Research, vol. 37, no. 5, pp. 446–451, 2012. View at Publisher · View at Google Scholar · View at Scopus
  19. K. Empen, R. Lorbeer, H. Völzke et al., “Do patients with type 1 and type 2 diabetes really have an impaired endothelial function? A population-based propensity score matching analysis,” Cardiovascular Diabetology, vol. 12, no. 1, article 174, 2013. View at Publisher · View at Google Scholar · View at Scopus
  20. P. Palazzo, P. Maggio, R. Altavilla et al., “Cerebral hemodynamics and systemic endothelial function are already impaired in well-controlled type 2 diabetic patients, with short-term disease,” PLoS ONE, vol. 8, no. 12, Article ID e83287, 2013. View at Publisher · View at Google Scholar · View at Scopus
  21. T. Maruhashi, J. Soga, N. Fujimura et al., “Relationship between flow-mediated vasodilation and cardiovascular risk factors in a large community-based study,” Heart, vol. 99, no. 24, pp. 1837–1842, 2013. View at Publisher · View at Google Scholar · View at Scopus
  22. M. T. Nguyen, I. Pham, P. Valensi et al., “Flow-mediated-paradoxical vasoconstriction is independently associated with asymptomatic myocardial ischemia and coronary artery disease in type 2 diabetic patients,” Cardiovascular Diabetology, vol. 13, no. 1, article 20, 2014. View at Publisher · View at Google Scholar · View at Scopus
  23. Y.-F. Liao, Y. Feng, L.-L. Chen, T.-S. Zeng, F. Yu, and L.-J. Hu, “Coronary heart disease risk equivalence in diabetes and arterial diseases characterized by endothelial function and endothelial progenitor cell,” Journal of Diabetes and Its Complications, vol. 28, no. 2, pp. 214–218, 2014. View at Publisher · View at Google Scholar · View at Scopus
  24. N. Kawano, M. Emoto, K. Mori et al., “Association of endothelial and vascular smooth muscle dysfunction with cardiovascular risk factors, vascular complications, and subclinical carotid atherosclerosis in type 2 diabetic patients,” Journal of Atherosclerosis and Thrombosis, vol. 19, no. 3, pp. 276–284, 2012. View at Publisher · View at Google Scholar · View at Scopus
  25. K. Suzuki, K. Watanabe, S. Futami-Suda et al., “The effects of postprandial glucose and insulin levels on postprandial endothelial function in subjects with normal glucose tolerance,” Cardiovascular Diabetology, vol. 11, article 98, 2012. View at Publisher · View at Google Scholar · View at Scopus
  26. S. Matsuo, E. Imai, M. Horio et al., “Revised equations for estimated GFR from serum creatinine in Japan,” American Journal of Kidney Diseases, vol. 53, no. 6, pp. 982–992, 2009. View at Publisher · View at Google Scholar · View at Scopus
  27. A. S. Levey, P. E. De Jong, J. Coresh et al., “The definition, classification, and prognosis of chronic kidney disease: a KDIGO controversies conference report,” Kidney International, vol. 80, no. 1, pp. 17–28, 2011. View at Publisher · View at Google Scholar · View at Scopus
  28. D. S. Keith, G. A. Nichols, C. M. Gullion, J. B. Brown, and D. H. Smith, “Longitudinal follow-up and outcomes among a population with chronic kidney disease in a large managed care organization,” Archives of Internal Medicine, vol. 164, no. 6, pp. 659–663, 2004. View at Publisher · View at Google Scholar · View at Scopus
  29. H. Ito, S. Antoku, M. Furusho et al., “The Prevalence of the risk factors for atherosclerosis among type 2 diabetic patients is greater in the progressive stages of chronic kidney disease,” Nephron Extra, vol. 3, no. 1, pp. 66–72, 2013. View at Publisher · View at Google Scholar
  30. H. Ito, M. Mifune, M. Abe et al., “Hypertension resistant to antihypertensive agents commonly occurs with the progression of diabetic nephropathy in Japanese patients with type 2 diabetes mellitus: a prospective observational study,” BMC Nephrology, vol. 13, article 48, 2012. View at Publisher · View at Google Scholar · View at Scopus
  31. H. Ito, H. Ohira, T. Chinen et al., “The ratio of serum eicosapentaenoic acid to arachidonic acid is associated with renal impairment and diabetic macroangiopathies in elderly patients with type 2 diabetes,” Diabetes Care, vol. 37, no. 1, pp. e7–e8, 2014. View at Publisher · View at Google Scholar · View at Scopus
  32. H. Ito, K. Oshikiri, M. Mifune et al., “The usefulness of the revised classification for chronic kidney disease by the KDIGO for determining the frequency of diabetic micro- and macroangiopathies in Japanese patients with type 2 diabetes mellitus,” Journal of Diabetes and its Complications, vol. 26, no. 4, pp. 286–290, 2012. View at Publisher · View at Google Scholar · View at Scopus
  33. H. Ito, Y. Takeuchi, H. Ishida et al., “High frequencies of diabetic micro-and macroangiopathies in patients with type 2 diabetes mellitus with decreased estimated glomerular filtration rate and normoalbuminuria,” Nephrology Dialysis Transplantation, vol. 25, no. 4, pp. 1161–1167, 2010. View at Publisher · View at Google Scholar · View at Scopus
  34. H. Yokoyama, H. Sone, K. Saito, D. Yamada, J. Honjo, and M. Haneda, “Flow-mediated dilation is associated with microalbuminuria independent of cardiovascular risk factors in type 2 diabetes: interrelations with arterial thickness and stiffness,” Journal of Atherosclerosis and Thrombosis, vol. 18, no. 9, pp. 744–752, 2011. View at Publisher · View at Google Scholar · View at Scopus
  35. H. Makino, K. Doi, A. Hiuge et al., “Impaired flow-mediated vasodilatation and insulin resistance in type 2 diabetic patients with albuminuria,” Diabetes Research and Clinical Practice, vol. 79, no. 1, pp. 177–182, 2008. View at Publisher · View at Google Scholar · View at Scopus
  36. M. Suetsugu, K. Takebayashi, and Y. Aso, “Association between diabetic microangiopathy and vascular endothelial function evaluated by flow-mediated vasodilatation in patients with type 2 diabetes,” International Journal of Clinical Practice, vol. 61, no. 6, pp. 920–926, 2007. View at Publisher · View at Google Scholar · View at Scopus
  37. W. B. Chan, N. N. Chan, C. W. K. Lai et al., “Vascular defect beyond the endothelium in type II diabetic patients with overt nephropathy and moderate renal insufficiency,” Kidney International, vol. 70, no. 4, pp. 711–716, 2006. View at Publisher · View at Google Scholar · View at Scopus
  38. A. Jawa, S. Nachimuthu, M. Pendergrass, S. Asnani, and V. Fonseca, “Impaired vascular reactivity in African-American patients with type 2 diabetes mellitus and microalbuminuria or proteinuria despite angiotensin-converting enzyme inhibitor therapy,” Journal of Clinical Endocrinology and Metabolism, vol. 91, no. 1, pp. 31–35, 2006. View at Publisher · View at Google Scholar · View at Scopus
  39. C. D. A. Stehouwer, R. M. A. Henry, J. M. Dekker, G. Nijpels, R. J. Heine, and L. M. Bouter, “Microalbuminuria is associated with impaired brachial artery, flow-mediated vasodilation in elderly individuals without and with diabetes: further evidence for a link between microalbuminuria and endothelial dysfunction—the Hoorn Study,” Kidney International, Supplement, vol. 66, no. 92, pp. S42–S44, 2004. View at Publisher · View at Google Scholar · View at Scopus
  40. K. K. Naka, K. Papathanassiou, A. Bechlioulis et al., “Determinants of vascular function in patients with type 2 diabetes,” Cardiovascular Diabetology, vol. 11, article 127, 2012. View at Publisher · View at Google Scholar · View at Scopus
  41. A. Taslipinar, H. Yaman, M. I. Yilmaz et al., “The relationship between inflammation, endothelial dysfunction and proteinuria in patients with diabetic nephropathy,” Scandinavian Journal of Clinical and Laboratory Investigation, vol. 71, no. 7, pp. 606–612, 2011. View at Publisher · View at Google Scholar · View at Scopus
  42. J.-S. Yun, S.-H. Ko, J.-H. Kim et al., “Diabetic retinopathy and endothelial dysfunction in patients with type 2 diabetes mellitus,” Diabetes & Metabolism Journal, vol. 37, no. 4, pp. 262–269, 2013. View at Publisher · View at Google Scholar
  43. R. Rossi, E. Cioni, A. Nuzzo, G. Origliani, and M. G. Modena, “Endothelial-dependent vasodilation and incidence of type 2 diabetes in a population of healthy postmenopausal women,” Diabetes Care, vol. 28, no. 3, pp. 702–707, 2005. View at Publisher · View at Google Scholar · View at Scopus