Longitudinal Analysis of Adiponectin through 20-Year Type 1 Diabetes Duration

Table 2

Results from the longitudinal model predicting log adiponectin.

Predictor	Estimate	value	Percent difference in adiponectin	95% CI for percent difference
Age, per 1 year
For females	0.019	0.002^*	1.9	1.1, 2.7
For males	0.010		1.0	0.3, 1.7
Female versus male
At 10 years of age	0.047	0.002^*
At 20 years	0.137		14.7	5.6, 24.5
At 30 years	0.226		25.3	13.0, 39.1
Tanner stage of 2	0.112	0.024	11.8	0.8, 24.1
Weight, per 5 kg	−0.038	0.004	3.7	2.3, 5.2
Waist, per 5 cm	−0.036	0.021	3.5	1.1, 5.8
HbA1c, per 1%	0.040	<0.0001	4.1	2.4, 5.6
HbA1c, per 10 mmol/mol	0.036	<0.0001	3.7	2.1, 4.7
(insulin dose), per 1 unit		0.030^*
At 1-year duration	0.169
At 4 years	0.093
At 7 years	0.016
At 9 years	−0.034
At 20 years	−0.314
(UACR), per 1 unit		<0.0001^*
At 1-year duration	−0.026
At 4 years	−0.009
At 7 years	0.008
At 9 years	0.019
At 20 years	0.082		8.5	5.4, 11.7

Results from repeated measures model with compound symmetry variance matrix and robust standard errors.
^*P value for interaction terms. Bold indicates significance at P < 0.05.