Longitudinal Analysis of Adiponectin through 20-Year Type 1 Diabetes Duration
Table 2
Results from the longitudinal model predicting log adiponectin.
Predictor
Estimate
value
Percent difference in adiponectin
95% CI for percent difference
Age, per 1 year
For females
0.019
0.002*
1.9
1.1, 2.7
For males
0.010
1.0
0.3, 1.7
Female versus male
At 10 years of age
0.047
0.002*
At 20 years
0.137
14.7
5.6, 24.5
At 30 years
0.226
25.3
13.0, 39.1
Tanner stage of 2
0.112
0.024
11.8
0.8, 24.1
Weight, per 5 kg
−0.038
0.004
3.7
2.3, 5.2
Waist, per 5 cm
−0.036
0.021
3.5
1.1, 5.8
HbA1c, per 1%
0.040
<0.0001
4.1
2.4, 5.6
HbA1c, per 10 mmol/mol
0.036
<0.0001
3.7
2.1, 4.7
(insulin dose), per 1 unit
0.030*
At 1-year duration
0.169
At 4 years
0.093
At 7 years
0.016
At 9 years
−0.034
At 20 years
−0.314
(UACR), per 1 unit
<0.0001*
At 1-year duration
−0.026
At 4 years
−0.009
At 7 years
0.008
At 9 years
0.019
At 20 years
0.082
8.5
5.4, 11.7
Results from repeated measures model with compound symmetry variance matrix and robust standard errors. *P value for interaction terms. Bold indicates significance at P < 0.05.