Sensitivity and Specificity Improvement in Abdominal Obesity Diagnosis Using Cluster Analysis during Waist Circumference Cut-Off Point Selection

Table 1

Risk factors aggregation according to Cluster Analysis and derivatives clusters. Maracaibo City Metabolic Syndrome Prevalence Syndrome, 2013.

Phenotypes	Cluster 1	Cluster 2	Cluster 3	Cluster 4	Cluster 5	Cluster 6
Normal-weight females	Size: 7.7%; HOMA2-IR = 3.56	Size: 92.7; HOMA2-IR = 1.47^*
Normal-weight males	Size: 15.1%; HOMA2-IR = 2.54; HOMA2-Bcell = 172.82; TAG = 180.99	Size: 84.9%; HOMA2-IR = 1.15; HOMA2-Bcell = 109.69; TAG = 84.65^*
Overweight females	Size: 24.1%; HOMA2-IR = 3.12; HOMA2-Bcell = 195.18	Size: 25.3%; HOMA2-IR = 0.97; HOMA2-Bcell = 85.14^*	Size: 50.6%; HOMA2-IR = 1.69; HOMA2-Bcell = 137.06^*
Overweight; males	Size: 18.3%; HOMA2-IR = 3.57; HOMA2-Bcell = 212.77	Size: 46.1%; HOMA2-IR = 1.80; HOMA2-Bcell = 144.05^*	Size: 35.6%; HOMA2-IR = 1.09; HOMA2-Bcell = 90.33^*
Obese Class I females	Size: 1.1%; HOMA2-IR = 10.30	Size: 4.8%; HOMA2-IR = 5.12	Size: 9.0%; HOMA2-IR = 3.95	Size: 31.4 %; HOMA2-IR = 1.16^*	Size: 35.1%; HOMA2-IR = 2.06	Size: 18.6%; HOMA2-IR = 2.86
Obese Class II females	Size: 1.2%; HOMA2-IR = 8.60	Size: 2.4%; HOMA2-IR = 8.40	Size: 3.6%; HOMA2-IR = 6.37	Size: 34.1%; HOMA2-IR = 1.38^*	Size: 32.9%; HOMA2-IR = 2.52	Size: 25.6%; HOMA2-IR = 3.66
Obese Class III females	Size: 4.8%; HOMA2-IR = 1.31	Size: 14.3%; HOMA2-IR = 4.5	Size: 2.4%; HOMA2-IR = 9.0	Size: 14.3%; HOMA2-IR = 3.67	Size: 31.0%; HOMA2-IR = 2.35	Size: 33.3 %; HOMA2-IR = 1.31^*
Obese Class I; male	Size: 1.0%; HOMA2-IR = 8.60	Size: 11.2%; HOMA2-IR = 4.60	Size: 19.8%; HOMA2-IR = 3.11	Size: 28.3%; HOMA2-IR = 2.19	Size: 26.3%; HOMA2-IR = 1.59^*	Size: 13.6%; HOMA2-IR = 0.93^*
Obese Class II male	Size: 2.7%; HOMA2-IR = 8.10	Size: 16.0%; HOMA2-IR = 3.36	Size: 26.7%; HOMA2-IR = 3.36	Size: 28.0%; HOMA2-IR = 1.71^*	Size: 17.3%; HOMA2-IR = 2.45	Size: 9.3%; HOMA2-IR = 0.70^*
Obese Class III male	Size: 2.6%; HOMA2-IR = 10.10	Size: 10.3%; HOMA2-IR = 7.02	Size: 15.4%; HOMA2-IR = 5.83	Size: 20.4%; HOMA2-IR = 4.11	Size: 38.5%; HOMA2-IR = 2.78	Size: 12-8%; HOMA2-IR = 1.52^*

The cells with “*” indicate the “healthy” clusters for each phenotype. The cells without “*” represent the “sick” clusters of persons.
HOMA2-IR: Homeostasis Model Assessment-2 for Insulin Resistance; HOMA2-Bcell: Homeostasis Model Assessment-2 for Pancreatic β Cell Function; TAG: triglycerides, expressed in mg/dL.