Sensitivity and Specificity Improvement in Abdominal Obesity Diagnosis Using Cluster Analysis during Waist Circumference Cut-Off Point Selection

Table 7

Waist circumference cut-offs based on ROC Curves. Sensitivity, Specificity, Youden’s Index, Positive Likelihood, and Distance to the ROC Curve. Maracaibo City Metabolic Syndrome Prevalence Syndrome, 2013.

	WC (cm)	Sensitivity (%)	Specificity (%)	Youden’s Index	Distance to ROC	LR+
6 phenotypes
Women	90.75	75.2	65.3	0.41	0.42	2.16
		73.3	68.5	0.42	0.41	2.32
	91.75	73.3	68.4	0.42	0.41	2.32
Men	97.75	76.5	67.8	0.44	0.40	2.37
	98.15	74.8	69.7	0.45	0.39	2.46
	98.40	74.5	69.7	0.44	0.40	2.45
4 phenotypes
Women	90.75	82.2	75.9	0.58	0.29	3.41
	91.5	80.1	79.3	0.60	0.28	3.86
	92.25	78.4	83.0	0.61	0.28	4.61
Men	97.50	85.7	80.2	0.66	0.24	4.32
	98.15	83.8	82.3	0.66	0.23	4.73
	98.40	83.5	82.3	0.66	0.24	4.71
2 phenotypes
Women	90.75	94.3	92.6	0.87	0.09	12.74
	91.5	93.4	93.7	0.88	0.09	14.82
	92.5	92.9	94.6	0.88	0.09	17.20
Men	97.00	96.0	98.5	0.95	0.04	64.00
	98.15	96.0	99.5	0.96	0.04	192.00
	98.65	95.5	99.5	0.95	0.05	191.00

6 phenotypes: HNW, MONW, MHO, MDO, and Overweight healthy and sick groups
4 phenotypes: HNW, MONW, and Overweight healthy and sick groups.
2 phenotypes: HNW and MDO.
() Selected cut-off (in cm) based on Sensitivity, Specificity, Youden Index, and Positive Likelihood Ratios (LR+), giving emphasis to highest sensitivity values.
() Cutpoint 1, asserted using the maximum Youden Index.
() Cutpoint 2, obtained from the point closet to the ROC (0.1).