Use of Drosophila as an Evaluation Method Reveals imp as a Candidate Gene for Type 2 Diabetes in Rat Locus Niddm22

Figure 1

Expression pattern of the GFP-tagged protein trap. imp expression in third instar larva was examined using a protein trap strain ZCL0310, which expresses GFP-Imp chimeric protein in endogenous imp-expressing tissues. Bright field (a, c) and intrinsic GFP (b, d) images are shown. The GFP signal was detected in the central nervous system (CNS) (a, b), but only in a subset of neurons within the CNS. In contrast, GFP-Imp was not confirmed in the fat body (c, d). Bar, 100 μm.

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