Psoriasis and Diabetes: A Multicenter Study in 222078 Type 2 Diabetes Patients Reveals High Levels of Depression

Table 3

Confounder-adjusted summary for diabetes-related complications, comorbidities, and comedication, stratified by psoriasis.

Adjusted estimates	Type 2 diabetes		value
	No psoriasis	Psoriasis
	221846	232	—
Depression, %	2.8 [2.7; 2.8]	10.5 [7.1; 15.2]	<0.0001
Hypertension, %	68.0 [67.8; 68.2]	86.1 [81.1; 90.0]	<0.0001
	( = 208211)	( = 226)
Autoimmune thyroid disease, %	4.6 [4.5; 4.7]	14.0 [10.1; 19.2]	<0.0001
	( = 221815)	( = 232)
Dyslipidemia, %	82.5 [82.3; 82.7]	80.8 [74.2; 85.9]	n.s.
	( = 168168)	( = 186)
Severe hypoglycemia, per patient year	0.06 [0.057; 0.060]	0.31 [0.238; 0.399]	<0.0001
	( = 221836)	( = 232)
Previous inpatient care, %	10.5 [10.4; 10.6]	20.2 [15.5; 26.0]	<0.0001
Duration of hospital stays, days per hospitalization	4.19 [4.18; 4.20]	7.67 [7.26; 8.11]	<0.0001
Comedication
Antihypertensive drugs, %	50.2 [50.0; 50.4]	76.5 [70.7; 81.4]	<0.0001
Steroids, %	1.5 [1.4; 1.5]	6.3 [3.8; 10.3]	<0.0001

Adjusted means or proportions with 95% confidence interval. Potential confounders are age, sex, and duration of diabetes. The number in parentheses indicates the patients studied. n.s.: not significant.