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Journal of Diabetes Research
Volume 2015 (2015), Article ID 798460, 11 pages
Research Article

Can the Onset of Type 2 Diabetes Be Delayed by a Group-Based Lifestyle Intervention in Women with Prediabetes following Gestational Diabetes Mellitus (GDM)? Findings from a Randomized Control Mixed Methods Trial

1School of Medicine, Clinical Sciences Institute, National University of Ireland Galway, Galway, Ireland
2School of Psychology, National University of Ireland Galway, Galway, Ireland
3HRB Clinical Research Facility, National University of Ireland Galway, Galway, Ireland
4Discipline of General Practice, School of Medicine, National University of Ireland Galway, Galway, Ireland
5Croí–The West of Ireland Cardiac Foundation, Croí Heart and Stroke Centre, Moyola Lane, Newcastle, Galway, Ireland
6J.E. Cairnes School of Business & Economics, National University of Ireland Galway, Cairnes Building, Galway, Ireland
7Cardiovascular Medicine, International Centre for Circulatory Health, Imperial College London, London W2 1LA, UK

Received 22 March 2015; Accepted 7 July 2015

Academic Editor: Ike S. Okosun

Copyright © 2015 Angela O’Dea et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Objective. To evaluate a 12-week group-based lifestyle intervention programme for women with prediabetes following gestational diabetes (GDM). Design. A two-group, mixed methods randomized controlled trial in which 50 women with a history of GDM and abnormal glucose tolerance postpartum were randomly assigned to intervention () or wait control () and postintervention qualitative interviews with participants. Main Outcome Measures. Modifiable biochemical, anthropometric, behavioural, and psychosocial risk factors associated with the development of type 2 diabetes. The primary outcome variable was the change in fasting plasma glucose (FPG) from study entry to one-year follow-up. Results. At one-year follow-up, the intervention group showed significant improvements over the wait control group on stress, diet self-efficacy, and quality of life. There was no evidence of an effect of the intervention on measures of biochemistry or anthropometry; the effect on one health behaviour, diet adherence, was close to significance. Conclusions. Prevention programmes must tackle the barriers to participation faced by this population; home-based interventions should be investigated. Strategies for promoting long-term health self-management need to be developed and tested.