Journal of Diabetes Research / 2015 / Article / Fig 10

Research Article

In Vitro and In Vivo Effects of Metformin on Osteopontin Expression in Mice Adipose-Derived Multipotent Stromal Cells and Adipose Tissue

Figure 10

The results of morphometric analyses: comparison of the adipocytes size (a) and areas (b) in tissue of control and experimental group. Differences in cells dimensions were statistically significant at (). Morphometric analysis of adipocytes was performed on six sections separately. Calculations were expressed as a mean value (-axis). (c) The results of hematoxylin-eosin (H-E) staining of adipose tissue sections derived from control group (A) and experimental group (B). Diversity of adipocytes in tissue of mice treated with metformin was indicated with arrows: red is indicating cells smaller in size and black is indicating cells of larger size. Scale bar is 75 μm. (d) The results of crown-like structures determination performed on six different microscopic images. Crown-like structures are visible in sections as aggregated macrophages accumulated and fused around adipocytes.
(a)
(b)
(c)
(d)

We are committed to sharing findings related to COVID-19 as quickly and safely as possible. Any author submitting a COVID-19 paper should notify us at help@hindawi.com to ensure their research is fast-tracked and made available on a preprint server as soon as possible. We will be providing unlimited waivers of publication charges for accepted articles related to COVID-19.