Research Article

The Impact of Abnormal Glucose Tolerance and Obesity on Fetal Growth

Table 2

Determinants of size for gestational age (LGA).

Odds ratio of LGA
(95% CI)
UnivariableFinal model

Prepregnancy BMI
 <18.50.59 (0.33, 1.07)0.58 (0.32, 0.94)
 18.5–24.9 (ref)
 25.0–30.01.37 (1.03, 1.81)1.34 (1.00, 1.79)
 30.0+1.44 (1.05, 1.98)1.53 (1.11, 2.12)

Age (per 1 year)1.01 (0.99, 1.04)

Preexisting CVD or hypertension
 Yes 1.01 (0.99, 1.04)
 No (ref)

Prepregnancy smoking
 Yes0.98 (0.84, 1.14)
 No (ref)

Parity
 0 (ref)
 1+1.11 (0.97, 1.26)

Height (for each 10 cm change)1.86 (1.54, 2.25)1.98 (1.62, 2.42)

Education
 Did not complete high school0.91 (0.59, 1.38)
 Completed high school only0.98 (0.70, 1.35)
 Education beyond high school (ref)

Income
 <$30,0000.83 (0.62, 1.12)
 $30,000–$80,000 (ref)
 $80,000+0.96 (0.78, 1.19)

Stress1.03 (0.91, 1.16)

Antidepressant use
 Yes1.85 (1.32, 2.60)1.71 (1.20, 2.44)
 No (ref)

Depression
 <16 on CES-D (ref)
 ≥16 on CES-D0.97 (0.82, 1.14)

Smoking during pregnancy
 Yes0.83 (0.65, 1.06)
 No (ref)

Hyper emesis
 Yes0.87 (0.73, 1.03)
 No (ref)

Exercise
 ≥3 times a week (ref)
 <3 times a week1.02 (0.89, 1.16)

Total kilocalories (per 100 kcal)1.01 (0.99, 1.02)

Percent kcals from fat (per 10%)1.20 (0.89, 1.60)

Vitamin D sufficiency
 Yes (ref)
 No0.95 (0.81, 1.13)

Grams of omega-3 (per 1 gram)0.89 (0.50, 1.61)

Weight gain
 Insufficient 0.57 (0.32, 1.00)0.52 (0.29, 0.94)
 Appropriate (ref)
 Excess 1.77 (1.25, 2.49)1.79 (1.25, 2.57)

Gestational diabetes
 None (ref)
 Abnormal glucose tolerance 2.28 (1.29, 4.02)2.84 (1.53, 5.27)
 Gestational diabetes0.80 (0.49, 1.30)0.65 (0.38, 1.12)

Insulin use
 Yes1.38 (0.93, 2.06)
 No (ref)

*Age, preexisting CVD or hypertension, prepregnancy smoking, parity, education, income, stress, depression, smoking during pregnancy, hyper emesis, exercise, total kilocalories, percent kilocalories from fat, vitamin D sufficiency, omega-3 fatty acid consumption, and insulin use did not reach statistical significance during the model building process.