Research Article

The Impact of Abnormal Glucose Tolerance and Obesity on Fetal Growth

Table 3

Determinants of fetal adiposity using weight/length ratio (linear regression).

Regression coefficients
(95% CI)
UnivariableFinal model

Prepregnancy BMI
 <18.5−1.72 (−3.88, 0.44)−1.52 (−3.63, 0.60)
 18.5–24.9 (ref)
 25.0–30.00.42 (−0.64, 1.49)0.38 (−0.67, 1.42)
 30.0+0.98 (−0.32, 2.28)1.35 (0.07, 2.64)

Age (per 1 year)0.13 (0.04, 0.21)

Preexisting CVD or hypertension
 Yes −0.87 (−3.22, 1.47)
 No (ref)

Prepregnancy smoking
 Yes−1.10 (−2.13, −0.06)
 No (ref)

Parity
 0 (ref)
 1+1.65 (0.76, 2.54)1.95 (1.07, 2.83)

Height (for each 10 cm change)2.17 (1.54, 2.79)2.12 (1.50, 2.74)

Education
 Did not complete high school−0.89 (−2.81, 1.03)
 Completed high school only−1.04 (−2.37, 0.30)
 Education beyond high school (ref)

Income
 <$30,000−0.01 (−1.41, 1.40)
 $30,000–$80,000 (ref)
 $80,000+0.27 (−0.65, 1.19)

Stress−0.15 (−0.58, 0.27)

Antidepressant use
 Yes2.23 (−1.43, 5.88)
 No (ref)

Depression
 <16 on CES-D (ref)
 ≥16 on CES-D−0.92 (−2.03, 0.19)

Smoking during pregnancy
 Yes−3.03 (−4.49, −1.56)−3.01 (−4.45, −1.57)
 No (ref)

Hyper emesis
 Yes−0.82 (−1.93, 0.29)
 No (ref)

Exercise
 ≥3 times a week (ref)
 <3 times a week−0.04 (−0.94, 0.86)

Total kilocalories (per 100 kcal)0.005 (−0.05, 0.06)

Percentage of kcals from fat (per 10%)0.54 (−0.44, 1.53)

Vitamin D sufficiency
 Yes (ref)
 No−0.37 (−1.54, 0.80)

Grams of omega-3 (per 1 gram)0.52 (−1.44, 2.49)

Weight gain
 Insufficient −2.16 (−4.30, −0.02)−2.42 (−4.54, −0.30)
 Appropriate (ref)
 Excess 2.01 (0.74, 3.27)2.15 (0.90, 3.40)

Gestational diabetes
 None (ref)
 Abnormal glucose tolerance 4.82 (1.09, 8.54)4.98 (1.34, 8.63)
 Gestational diabetes−0.05 (−2.53, 2.44)0.03 (−2.42, 2.48)

Insulin use
 Yes0.49 (−2.69, 3.95)
 No (ref)

*Age, preexisting CVD or hypertension, prepregnancy smoking, parity, education, income, stress, antidepressant use, depression, hyper emesis, exercise, total kilocalories, percent kilocalories from fat, vitamin D sufficiency, omega-3 fatty acid consumption, and insulin use did not reach statistical significance during the model building process.