Table 4: (a) PPARGC1A SNP association with T2D in Haitian Americans. (b) PPARGC1A SNP association with T2D in African Americans.
(a)

VariablesHaitian American
Unadjusted OR95% CI valueAdjusted OR95% CI value

rs8192678 TT + CT versus CC0.660.301.420.2850.490.151.600.228
rs7656250CC + CT versus TT0.660.341.300.2310.220.070.640.005
rs4235308CC + CT versus TT0.530.300.950.0330.420.170.930.026
rs11724367CC + CG versus GG1.140.522.520.7451.730.555.490.353
rs8192678    sex 1.770.349.270.490
rs7656250    sex7.531.6634.150.008
rs4235308    sex1.560.465.340.444
rs11724367    sex0.540.092.950.483

Note: the statistically significant results are in bold. Controlled variables included in the logistic regression analysis for adjusted OR were age, sex, BMI, and smoking status. The interactions between sex and individual SNP were also included in logistic regression analysis for all the SNP. is considered significant at 0.05. OR: odds ratio; CI: confidence interval; PPARGC1A: peroxisome proliferator activated receptor, gamma, coactivator 1 alpha.
(b)

Variables African American
Unadjusted OR95% C.I.valueAdjusted OR95% C.I. value

rs8192678TT + CT versus CC0.900.451.870.7770.550.191.560.269
rs7656250CC + CT versus TT0.620.341.130.1171.020.432.430.940
rs4235308CC + CT versus TT1.290.752.210.3562.531.085.920.028
rs11724367CC + CG versus GG0.690.331.250.3290.290.081.140.073
rs8192678    sex1.460.385.600.585
rs7656250    sex0.360.111.130.079
rs4235308    sex0.480.151.590.220
rs11724367    sex3.780.8217.310.082

Note: the statistically significant results are in bold. Controlled variables included in the logistic regression analysis for adjusted OR were age, sex, BMI, and smoking status. The interactions between sex and individual SNP were also included in logistic regression analysis for all the SNP. is considered significant at 0.05. OR: odds ratio; CI: confidence interval; PPARGC1A: peroxisome proliferator activated receptor, gamma, coactivator 1 alpha.