Journal of Diabetes Research / 2015 / Article / Fig 1

Review Article

Impaired Adipose Tissue Expandability and Lipogenic Capacities as Ones of the Main Causes of Metabolic Disorders

Figure 1

Lipogenic pathway in obese patients. The loss of the lipogenic capacity of the adipose tissue is compensated by other tissues and organs, mainly the liver. Thus, many molecules come into play in this loss of lipogenic capacity of the adipose tissue, acting in a wrong way. HFD: high fat diet; IR: insulin resistance; TAG: triacylglycerol; PPARγ: peroxisome proliferator-activated receptor-γ; FASN: fatty acid synthase; ZAG: zinc-α2 glycoprotein; FABP4: fatty acid-binding protein 4; RORγ1: retinoic acid receptor-related orphan nuclear receptor γ1; SCD1: stearoyl-CoA desaturase-1; Rab18: Ras-related protein 18; BrCa1: breast cancer 1.

We are committed to sharing findings related to COVID-19 as quickly and safely as possible. Any author submitting a COVID-19 paper should notify us at to ensure their research is fast-tracked and made available on a preprint server as soon as possible. We will be providing unlimited waivers of publication charges for accepted articles related to COVID-19.