Research Article

Testicular Metabolic Reprogramming in Neonatal Streptozotocin-Induced Type 2 Diabetic Rats Impairs Glycolytic Flux and Promotes Glycogen Synthesis

Table 3

Metabolite content of testicular tissue in animals from the control (CTR) and T2DM group.

Metabolites (nmol/mg tissue)CTRT2DM

Lactate2.90 ± 0.601.45 ± 0.30
Alanine0.70 ± 0.200.73 ± 0.20
Glycogen0.25 ± 0.030.41 ± 0.10
UDP-Glucose0.48 ± 0.010.54 ± 0.01

Lactate/Alanine ratio3.70 ± 0.302.70 ± 0.40

Legend: CTR: control; T2DM: type 2 diabetes mellitus. Results are expressed as mean ± SEM ( for each condition). Significantly different relative to control ().