Combination Therapy with Oleanolic Acid and Metformin as a Synergistic Treatment for Diabetes

Figure 4

Histological analysis using H&E and PAS staining after 4 weeks of treatment with oleanolic acid, metformin, and the combination. (a) Representative photomicrographs depicting the H&E staining of liver sections in untreated and treated db/db mice. (b) Representative photomicrographs depicting the PAS staining of liver sections in untreated and treated db/db mice. (c) Liver glycogen. versus untreated db/db mice. versus untreated db/db mice. versus oleanolic acid-treated db/db mice. Each bar represents the mean ± SEM of the group ().

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