Combination Therapy with Oleanolic Acid and Metformin as a Synergistic Treatment for Diabetes

Figure 5

Histological analysis using immunofluorescence staining after 4 weeks of treatment with oleanolic acid, metformin, or the combination. (a) Double immunofluorescence of α-actin (green fluorescence) and G-6-Pase (red fluorescence) from the pancreas of different groups; merged figures are shown on the right. (b) Double immunofluorescence of α-actin (green fluorescence) and PEPCK1 (red fluorescence) from the pancreas of different groups; merged figures are shown on the right.

(a)

(b)