Research Article

Serum Magnesium Concentration Is Inversely Associated with Albuminuria and Retinopathy among Patients with Diabetes

Table 2

Association of serum Mg2+ with albuminuria and retinopathy.

Mg2+ (mmol/L)Isolated albuminuriaIsolated retinopathyAlbuminuria and retinopathy
OR (95% CI)OR (95% CI)OR (95% CI)
Model 1Model 2Model 1Model 2Model 1Model 2

0.7–0.79 111111
0.8–0.89 0.67 (0.49–0.90)0.83 (0.58–1.19)0.81 (0.60–1.09)0.81 (0.57–1.15)0.69 (0.49–0.99)0.76 (0.49–1.17)
0.9–1.00.55 (0.41–0.75)0.64 (0.44–0.92)0.65 (0.48–0.88)0.68 (0.47–0.97)0.40 (0.27–0.58)0.58 (0.37–0.91)
P value for trend<0.0010.0090.0040.030<0.0010.014

Per 0.1 mmol/L0.76 (0.65–0.88)0.79 (0.66–0.94)0.81 (0.70–0.93)0.83 (0.69–0.98)0.62 (0.52–0.75)0.76 (0.61–0.95)

Model 1: adjusted for gender, age, and duration of diabetes; Model 2: adjusted for gender, age, duration of diabetes, hypertension, BMI, HbA1c, TC, TG, and CRP.
Age, duration of diabetes, BMI, HbA1c, TC, TG, and CRP were analysed as continuous variables.
OR: odds ratio, 95% CI: 95% confidence interval, BMI: body mass index, TC: total cholesterol, TG: triglyceride, and CRP: C-reactive protein. ; .