Incretin-Based Therapy for Prevention of Diabetic Vascular Complications

Figure 1

Overexpression of PKCβ2 in mouse glomerular endothelial cells (EC-PKCβ2Tg) and decreased glucagon-like peptide-1 receptors in diabetes. (a) Immunostaining of GLP-1R and CD31, showing merged images of the glomeruli. (b) Immunoblots of GLP-1R from renal cortex of mice. Images are reproduced from Mima et al. [11], with permission from Diabetes ©2012.

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