ALDH2 Inhibition Potentiates High Glucose Stress-Induced Injury in Cultured Cardiomyocytes

Figure 2

Disulfiram (DSF) pretreatment and ALDH2 activity. DSF 10 μM reduces ALDH2 activity in both HG and Ctrl groups. The data expressed are mean ± SEM. = 4–6. G1, G2, G3, and G4 depict mannitol, high glucose stress, DSF + mannitol, and DSF + high glucose stress. G1, G2, G3, and G4 depict mannitol, high glucose stress, DSF + mannitol, and DSF + high glucose stress, respectively. versus G1, versus G2, and versus G3.