Research Article

Swimming Exercise Alleviated Insulin Resistance by Regulating Tripartite Motif Family Protein 72 Expression and AKT Signal Pathway in Sprague-Dawley Rats Fed with High-Fat Diet

Figure 1

The signaling pathway of high-fat diet induced IR through TRIM72 and PI3-K/AKT in skeletal muscle. Whether the swimming exercise can improve insulin resistance in Sprague-Dawley rats fed with high-fat diet through inhibiting TRIM72 expression and activating PI3-K/AKT signal pathway should be further testified.