Research Article
Fatty Liver and Insulin Resistance in the Liver-Specific Knockout Mice of Mitogen Inducible Gene-6
Figure 5
The activation of insulin signaling pathways and PPARγ phosphorylation in Mig-6f/f and Mig-6d/d mice. The activities of insulin signaling were measured by western blotting using anti-p-IR, anti-IR, and anti-GAPDH antibodies. (a) In the liver (fasting or insulin injection after fasting condition). (b) In the reproductive fat (fasting condition). (c) PPARγ phosphorylation measured by western blotting using anti-p-PPARγ, anti-PPARγ, and anti-histone antibodies in reproductive fat.
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