The Relationships between Anabolic Hormones and Body Composition in Middle-Aged and Elderly Men with Prediabetes: A Cross-Sectional Study
Table 1
Characteristics of men with PD and control group.
Parameter
Prediabetes number 84
Control number 58
Age (years)
66.5 ± 3.8
65.7 ± 3.8
—
TT (nmol/L)
11.24 ± 1.81
16.23 ± 1.6
0.001
cFT (nmol/L)
0.331 ± 0.08
0.387 ± 0.07
0.005
DHEAS (ng/mL)
542 (186–867)
669 (229–943)
0.02
IGF-1, (ng/mL)
87.3 ± 43.3
94.3 ± 41.9
—
LH (IU/L)
6.7 ± 0.9
4.4 ± 1.2
0.05
FSH (IU/L)
8.2 ± 1.1
7.9 ± 1.3
—
Prolactin (ng/mL)
11 ± 3.8
12 ± 3.7
—
Estradiol (pg/mL)
31.9 ± 8.2
28.6 ± 7.8
0.05
SHBG (nmol/L)
31.8 ± 3.2
27.7 ± 3.4
0.02
Weight (kg)
86.2 ± 7.45
84.8 ± 6.75
—
BMI (kg/m2)
28.6 ± 1.2
27.8 ± 0.9
—
WC (cm)
111 (103–115)
98 (94–104)
0.01
HbA1c (%)
6.2 ± 0.9
5.2 ± 1.2
0.02
FPG (mg/dL)
116 ± 6.6
92 ± 4.6
0.001
Glucose in OGTT (mg/dL)
148 ± 6.4
117 ± 6.6
0.05
SBP (mmHg)
146 ± 17.2
139 ± 17.3
—
DBP (mmHg)
94 ± 12.4
90 ± 8.7
—
Cholesterol (mg/dL)
225 ± 18
202 ± 17
0.05
Triglycerides (mg/dL)
162 ± 13
151 ± 14
0.05
HDL-cholesterol (mg/dL)
36 ± 4.6
39 ± 4.2
—
LDL-cholesterol (mg/dL)
146 ± 12
132 ± 13
0.02
Comorbidities
Obesity, %; (number)
71 (60)
57 (33)
0.02
Current smoker, %, (number)
32 (27)
33 (19)
NS
Hypertension, %, (number)
51 (43)
38 (22)
0.05
MetS, %, (number)
83 (70)
67 (39)
0.01
CVD, %, (number)
26 (22)
19 (11)
0.05
Data are presented as a mean ± standard deviation of the mean, a median (with lower and upper quartiles), or number (percentage), where appropriate. shows differences between men with PD and control group. BMI: body mass index, WC: waist circumference, TT: total testosterone, cFT: calculated free testosterone, LH: luteinizing hormone, DHEAS: dehydroepiandrosterone sulfate, SHBG: sex hormone binding globulin, E2: estradiol, IGF-1: insulin-like growth factor 1, FPG: fasting plasma glucose, OGTT: oral glucose tolerance test, HbA1c: glycated hemoglobin, MetS: metabolic syndrome, CVD: cardiovascular disease, SBP: systolic blood pressure, and DBP: diastolic blood pressure.