Clinical Study

The Relationships between Anabolic Hormones and Body Composition in Middle-Aged and Elderly Men with Prediabetes: A Cross-Sectional Study

Table 1

Characteristics of men with PD and control group.

ParameterPrediabetes
number 84
Control
number 58

Age (years)66.5 ± 3.865.7 ± 3.8
TT (nmol/L)11.24 ± 1.8116.23 ± 1.60.001
cFT (nmol/L)0.331 ± 0.080.387 ± 0.070.005
DHEAS (ng/mL)542 (186–867)669 (229–943)0.02
IGF-1, (ng/mL)87.3 ± 43.394.3 ± 41.9
LH (IU/L)6.7 ± 0.94.4 ± 1.20.05
FSH (IU/L)8.2 ± 1.17.9 ± 1.3
Prolactin (ng/mL)11 ± 3.812 ± 3.7
Estradiol (pg/mL)31.9 ± 8.228.6 ± 7.80.05
SHBG (nmol/L)31.8 ± 3.227.7 ± 3.40.02
Weight (kg)86.2 ± 7.4584.8 ± 6.75
BMI (kg/m2)28.6 ± 1.227.8 ± 0.9
WC (cm)111 (103–115)98 (94–104)0.01
HbA1c (%)6.2 ± 0.95.2 ± 1.20.02
FPG (mg/dL) 116 ± 6.692 ± 4.60.001
Glucose in OGTT (mg/dL) 148 ± 6.4117 ± 6.60.05
SBP (mmHg)146 ± 17.2139 ± 17.3
DBP (mmHg)94 ± 12.490 ± 8.7
Cholesterol (mg/dL)225 ± 18202 ± 170.05
Triglycerides (mg/dL)162 ± 13151 ± 140.05
HDL-cholesterol (mg/dL)36 ± 4.639 ± 4.2
LDL-cholesterol (mg/dL)146 ± 12132 ± 130.02

Comorbidities
Obesity, %; (number)71 (60)57 (33)0.02
Current smoker, %, (number)32 (27)33 (19) NS
Hypertension, %, (number)51 (43)38 (22)0.05
MetS, %, (number)83 (70)67 (39)0.01
CVD, %, (number)26 (22)19 (11)0.05

Data are presented as a mean ± standard deviation of the mean, a median (with lower and upper quartiles), or number (percentage), where appropriate. shows differences between men with PD and control group. BMI: body mass index, WC: waist circumference, TT: total testosterone, cFT: calculated free testosterone, LH: luteinizing hormone, DHEAS: dehydroepiandrosterone sulfate, SHBG: sex hormone binding globulin, E2: estradiol, IGF-1: insulin-like growth factor 1, FPG: fasting plasma glucose, OGTT: oral glucose tolerance test, HbA1c: glycated hemoglobin, MetS: metabolic syndrome, CVD: cardiovascular disease, SBP: systolic blood pressure, and DBP: diastolic blood pressure.