Vitamin B6 Prevents Endothelial Dysfunction, Insulin Resistance, and Hepatic Lipid Accumulation in Apoe^−/− Mice Fed with High-Fat Diet

Table 1

Serum sugar and lipid levels in Apoe^−/− mice.

	WT	Apoe^−/−
	ND	ND	HFD	HFD + VitB6
Glucose (mM)	6.5 ± 1.3	8.2 ± 1.3	13.5 ± 0.8	10.2 ± 0.9
Cholesterol (mM)	3.7 ± 0.5	10.5 ± 2.1	28.4 ± 5.3	26.4 ± 4.9
Triglyceride (mM)	0.7 ± 0.2	0.8 ± 0.2	1.6 ± 0.3	1.5 ± 0.5
HDL-C (mg/L)	128 ± 15	252 ± 30	267 ± 38	257 ± 39
LDL-C (mg/L)	109 ± 14	249 ± 23	417 ± 53	435 ± 67

After 8-week administration of VitB6 in Apoe^−/− mice fed with high-fat diet, serum sugar levels and lipid levels were determined. WT: wild-type; ND: normal diet; HFD: high-fat diet; HDL: high density lipoprotein; LDL: low density lipoprotein. All data were expressed as mean ± SEM. is 10–15 in each group. versus Apoe^−/− mice fed with HFD.